Free practice questions · Infection control

Infection control practice questions.

Standard and transmission-based precautions, isolation, PPE, hand hygiene and sterile technique. Ten questions from the Lumen Nursing NCLEX-RN bank. Answer each one and check it; the rationale explains the key and every other option.

1Select all that applyFundamentals

The nurse is observing a nursing student set up a sterile field to change the dressing on a 60-year-old client's abdominal incision. Which of the following actions by the student would require the nurse to intervene?

Pours sterile 0.9% sodium chloride into a sterile basin without touching the basin
Holds wet sterile forceps with the tips pointing upward while cleaning the incision
Drops a sterile gauze pad onto the field about half an inch from its edge
Turns away from the field to answer the client's question about pain medication
Opens the first flap of the sterile kit away from the body before the side flaps
Answer it, then check it.
Answer and rationale
Answer
  • B: Holds wet sterile forceps with the tips pointing upward while cleaning the incision
  • C: Drops a sterile gauze pad onto the field about half an inch from its edge
  • D: Turns away from the field to answer the client's question about pain medication
The key, and why
Surgical asepsis keeps an area free of all microorganisms. A sterile field stays sterile only while it is in view, above waist level, and touched only by sterile items, and its outer inch is considered contaminated because it borders unsterile surfaces. A gauze pad landing half an inch from the edge is inside that contaminated border and is no longer sterile. Turning away means the field is out of sight and could be contaminated without anyone knowing, so it is treated as contaminated. Wet forceps held tips up let fluid run from the tips to the unsterile handle and back down onto the tips, carrying organisms with it; forceps are held tips down.
Each distractor
Option A is correct technique. Pouring from a few inches above the basin without touching it keeps the bottle lip, which is not sterile, from contacting the field. Option E is correct technique. The first flap is opened away from the body so that the nurse does not reach across the sterile inside of the kit.
The teaching point
STERILE FIELD → 1 inch BORDER is contaminated → keep it IN VIEW and ABOVE THE WAIST → never turn your back. Wet forceps → TIPS DOWN. Pour without touching. First flap AWAY from you. In doubt = contaminated.
2Multiple choice, single answerFundamentals

While the nurse is drawing blood from a client with HIV infection, a specimen tube cracks and a small amount of blood spills onto the bedside table. Which action should the nurse take to clean the spill?

Wipe the blood with a damp paper towel and discard it in the regular trash
Wear gloves, absorb the blood and disinfect with a 1:10 bleach solution
Spray the table with alcohol and wipe it dry with a paper towel
Cover the spill with a towel and leave it for environmental services
Answer it, then check it.
Answer and rationale
Answer
  • B: Wear gloves, absorb the blood and disinfect with a 1:10 bleach solution
The key, and why
Blood is treated as potentially infectious from every client, and this spill comes from a client known to have HIV. The goal is to remove the blood safely and then disinfect the surface. The nurse puts on gloves, and eye protection if there is any risk of splashing, absorbs the blood with disposable towels, then cleans the area with a freshly made 1:10 dilution of household bleach, about one part bleach to nine parts water, or with an approved hospital disinfectant, and leaves it wet for the contact time on the label. The soaked towels go in a biohazard bag, and the gloves are removed and the hands washed. Any broken glass is picked up with tongs or a dustpan, never by hand.
Each distractor
Option A handles blood without gloves and puts it in the ordinary trash. Option C uses alcohol, which is not an approved disinfectant for a blood spill, and leaves the blood on the surface. Option D leaves blood on a bedside table for hours, where the client, visitors and staff can touch it.
The teaching point
Blood spill = GLOVES, ABSORB, then DISINFECT with 1:10 BLEACH or an approved disinfectant. Contaminated towels in a BIOHAZARD bag. Glass with TONGS, never hands. STANDARD PRECAUTIONS for every client's blood, not only clients known to have HIV.
3Matrix gridAdult Health

The nurse is caring for a client receiving chemotherapy whose absolute neutrophil count is 400/mm3 and platelet count is 18,000/mm3. For each intervention below, click to specify whether the intervention is intended to prevent infection or to prevent bleeding.

Finding
Prevent infection
Prevent bleeding
Remove fresh flowers and plants from the room
Use an electric razor for shaving
Avoid intramuscular injections
Screen visitors for colds and other infections
Give acetaminophen instead of aspirin for pain
Report a temperature of 38.0 C (100.4 F) or higher at once
Answer it, then check it.
Answer and rationale
Answer
  • Remove fresh flowers and plants from the room: Prevent infection
  • Use an electric razor for shaving: Prevent bleeding
  • Avoid intramuscular injections: Prevent bleeding
  • Screen visitors for colds and other infections: Prevent infection
  • Give acetaminophen instead of aspirin for pain: Prevent bleeding
  • Report a temperature of 38.0 C (100.4 F) or higher at once: Prevent infection
The key, and why
The two problems need different protection. Neutropenia leaves the client unable to fight infection, so the measures keep germs away and catch infection early. Flowers and plants carry bacteria and molds, visitors with colds bring viruses, and a fever may be the only sign of a serious infection, because the client cannot form pus. Thrombocytopenia leaves the client unable to stop bleeding, so the measures prevent injury and avoid anything that impairs clotting. A blade razor can cut the skin, an intramuscular injection can bleed into the muscle, and aspirin blocks platelet function.
Each distractor
Placing the flowers or visitor screening under bleeding misreads them. These measures prevent infection. Placing the razor, the injections or the aspirin under infection misreads them. These measures prevent bleeding. Placing the fever report under bleeding misses its meaning. A fever in neutropenia is an emergency because it may signal sepsis.
The teaching point
NEUTROPENIA = prevent INFECTION. Hand hygiene, NO flowers, SCREEN visitors, REPORT FEVER. THROMBOCYTOPENIA = prevent BLEEDING. ELECTRIC razor, NO IM injections, NO ASPIRIN, SOFT toothbrush.
4Select all that applyMental Health

The charge nurse on an inpatient psychiatric unit is orienting a newly hired nurse who will observe a client on suicide precautions with checks every 15 minutes. Which of the following statements by the newly hired nurse would require follow-up?

"I will stop the checks overnight once the client has fallen asleep in bed."
"I will look in the client's mouth and hands after each oral medication is given."
"I will remove the drawstring from the sweatpants that the client's mother brought."
"I will search the client's room again after the client's visitors have left the unit."
"I will do the checks at exactly 0900, 0915, 0930, and 0945 so they are evenly spaced."
Answer it, then check it.
Answer and rationale
Answer
  • A: "I will stop the checks overnight once the client has fallen asleep in bed."
  • E: "I will do the checks at exactly 0900, 0915, 0930, and 0945 so they are evenly spaced."
The key, and why
Checks every 15 minutes are the lowest level of suicide observation. They work only if they are unpredictable, thorough, and continued around the clock, and only if the room stays free of anything the client could use for self-harm. Checks done at exactly the same minutes every quarter hour teach the client how long the gap is and when the nurse will not be looking. The checks are staggered at irregular times within each 15-minute window. Checks also continue through the night, and a sleeping client is seen well enough to confirm breathing and that the client is in fact asleep, because night hours with fewer staff are a high-risk time.
Each distractor
Option B is correct practice. Checking the mouth and hands after oral medications stops the client from hoarding tablets for an overdose. Option C is correct practice. A drawstring is a ligature risk, so drawstrings, belts, and shoelaces are removed, whoever brought them. Option D is correct practice. Visitors can bring in items, knowingly or not, so the room and belongings are checked after visits.
The teaching point
15-minute checks = IRREGULAR times, 24 HOURS a day, including while ASLEEP. REMOVE drawstrings, belts, shoelaces, and plastic bags. CHECK the mouth after oral medications. SEARCH again after visitors.
5Ordered responsePharmacology

While dropping a used needle into the sharps container after giving an IM injection to a client with HIV infection, the nurse sustains a puncture wound to the finger through the glove. Place the following actions in the order the nurse should perform them.

Drag the responses into the order you want. Drag one back to the list to remove it.
Your order
1Drag a response here
2Drag a response here
3Drag a response here
4Drag a response here
5Drag a response here
Responses
Report the exposure to the charge nurse and employee health immediately
Remove the gloves
Wash the puncture site with soap and running water
Begin postexposure prophylaxis as prescribed, ideally within 2 hours of the exposure
Complete an incident report describing how the exposure happened
Answer it, then check it.
Answer and rationale
Answer
  • 1: Remove the gloves
  • 2: Wash the puncture site with soap and running water
  • 3: Report the exposure to the charge nurse and employee health immediately
  • 4: Begin postexposure prophylaxis as prescribed, ideally within 2 hours of the exposure
  • 5: Complete an incident report describing how the exposure happened
The key, and why
A needlestick from a client with HIV infection carries a small but real risk of transmission, about 0.3% without treatment, and postexposure prophylaxis cuts that risk sharply when it is started early. The sequence protects the nurse first and then gets the drugs started as fast as possible. The gloves come off so the wound can be reached, and the site is washed with soap and running water. The nurse then reports the exposure immediately, so employee health or the emergency department can assess the risk, test the nurse and the source client with consent and prescribe prophylaxis. Postexposure prophylaxis, usually a three-drug antiretroviral regimen taken for 28 days, works best when it begins within hours, ideally within 2 hours and no later than 72 hours. The incident report is completed afterward, once treatment has started.
Each distractor
Washing before the gloves are removed cleans the glove instead of the wound. Reporting before washing leaves blood and body fluid in the wound for longer than needed. Starting prophylaxis before reporting is not possible, because the drugs are prescribed after the exposure has been reported and assessed. Completing the incident report before treatment delays the prophylaxis, which is the time-sensitive step.
The teaching point
NEEDLESTICK = gloves OFF → WASH with soap and water → REPORT immediately → PEP ideally within 2 HOURS (no later than 72) → incident REPORT. Do NOT squeeze the wound or use bleach.
Safety note
Never recap a used needle. Dispose of it directly into a sharps container at the point of use.
6Multiple choice, single answerPharmacology

The clinic nurse is reviewing the medications of a 70-year-old client who is prescribed ciprofloxacin 500 mg orally every 12 hours for a urinary tract infection. The client also takes a calcium carbonate supplement with breakfast at 0800 and with lunch at 1200 for osteoporosis. Which plan for taking ciprofloxacin should the nurse recommend?

Take ciprofloxacin at 0600 and 1800, at least 2 hours before or 6 hours after the calcium
Take ciprofloxacin at 0800 and 2000 with a glass of milk to prevent an upset stomach
Take ciprofloxacin at 1200 and 2400, and stop taking the calcium until the infection clears
Take ciprofloxacin at 0800 and 2000, swallowing the morning dose with the calcium supplement
Answer it, then check it.
Answer and rationale
Answer
  • A: Take ciprofloxacin at 0600 and 1800, at least 2 hours before or 6 hours after the calcium
The key, and why
Ciprofloxacin is a fluoroquinolone antibiotic. Calcium, magnesium, aluminum, iron, and zinc bind to fluoroquinolones in the gut and form a complex the body cannot absorb, so much less antibiotic reaches the blood and the infection may not clear. The same happens with tetracyclines. The fix is to separate them. Ciprofloxacin is taken at least 2 hours before or 6 hours after calcium, antacids, iron, zinc, and dairy foods taken on their own. A dose at 0600 is 2 hours before the 0800 calcium, and a dose at 1800 is 6 hours after the 1200 calcium, so both doses are absorbed and the 12-hour spacing stays.
Each distractor
Option B takes ciprofloxacin with milk. The calcium in milk binds the drug the same way the supplement does. Option C takes the noon dose with the lunchtime calcium, and it stops a prescribed supplement without the provider. Spacing the doses lets the client keep both. Option D takes the morning dose together with calcium, which blocks its absorption.
The teaching point
FLUOROQUINOLONES and TETRACYCLINES bind CALCIUM, MAGNESIUM, ALUMINUM, IRON, ZINC. Separate = antibiotic at least 2 HOURS BEFORE or 6 HOURS AFTER (ciprofloxacin). No milk, yogurt, or antacid with the dose.
7Multiple choice, single answerPharmacology

The clinic nurse receives a call from a 48-year-old client who has taken isoniazid 300 mg orally daily for latent tuberculosis infection for 2 months. The client reports 4 days of poor appetite, nausea, dark amber urine, and an ache under the right ribs. Which action should the nurse take?

Advise the client to take isoniazid with a large meal to settle the stomach
Recommend an over-the-counter antacid taken together with each daily dose
Explain that dark urine is an expected effect of the medication and will fade
Instruct the client to hold isoniazid and come in today for liver function tests
Answer it, then check it.
Answer and rationale
Answer
  • D: Instruct the client to hold isoniazid and come in today for liver function tests
The key, and why
Isoniazid can cause hepatitis, and the risk rises with age, daily alcohol use, other liver disease and other drugs that affect the liver. Most cases appear in the first months. Loss of appetite, nausea, dark urine and pain in the right upper abdomen are the warning signs, and jaundice may follow. A client who keeps taking isoniazid with these symptoms can develop liver failure. That is why every client on isoniazid is taught to stop the drug and call as soon as these symptoms begin, and why the nurse arranges liver function tests the same day. The health care provider decides whether and how treatment can continue. Pyridoxine (vitamin B6) is often given with isoniazid, but it prevents nerve damage, not liver injury.
Each distractor
Option A keeps the client on a drug that may be injuring the liver. Isoniazid is also best absorbed on an empty stomach. Option B treats the nausea as indigestion. Antacids containing aluminum also reduce the absorption of isoniazid, so they are taken at a different time. Option C confuses isoniazid with rifampin. Rifampin colors urine orange-red, which is harmless, but dark amber urine with nausea and right upper quadrant pain is a sign of liver injury.
The teaching point
ISONIAZID = HEPATITIS. Anorexia, nausea, DARK urine, RUQ pain, JAUNDICE = HOLD and get LFTs. ISONIAZID = PERIPHERAL NEUROPATHY too, prevented with PYRIDOXINE (B6). NO ALCOHOL during treatment.
8Multiple choice, single answerCritical Care

The nurse in the intensive care unit is caring for a 70-year-old client on day 4 of vancomycin 1,250 mg IV every 12 hours for methicillin-resistant Staphylococcus aureus (MRSA) pneumonia. The creatinine has risen from 1.0 mg/dL on admission to 1.9 mg/dL, and the trough level drawn 30 minutes ago is 26 mcg/mL (unit protocol target 15 to 20 mcg/mL). The next dose is due now. Which action should the nurse take?

Hold the dose and report the trough and creatinine to the health care provider
Infuse the dose over 2 hours instead of 1 hour
Give half of the dose now and the other half in 6 hours
Give the dose as scheduled and recheck the trough level before the next dose
Answer it, then check it.
Answer and rationale
Answer
  • A: Hold the dose and report the trough and creatinine to the health care provider
The key, and why
Vancomycin is an antibiotic used to treat serious bacterial infections, including MRSA. Vancomycin is cleared almost entirely by the kidneys, and at high levels it injures the kidney tubules. The two problems feed each other. As the kidneys fail, the medication builds up, and the higher level damages the kidneys further. A trough is the lowest level, drawn just before a dose, and it shows how much medication is still in the blood when the next dose would be added. This trough of 26 mcg/mL is above the target, and the creatinine has nearly doubled. Giving the dose now would push the level even higher. The nurse holds it and reports both results so the health care provider and pharmacist can lengthen the interval, lower the dose, or change the antibiotic.
Each distractor
Option B slows the infusion, which helps prevent a vancomycin infusion reaction with flushing. It does not lower the total amount of medication the kidneys must clear. Option C changes the dose and timing on the nurse's own authority. Dosing changes need a new prescription, usually guided by the pharmacist. Option D gives a dose on top of a level that is already too high, adding to the kidney injury.
The teaching point
VANCOMYCIN = cleared by the KIDNEYS and toxic to them. Trough HIGH + creatinine RISING = HOLD the dose and REPORT. Trough is drawn just BEFORE the dose.
Safety note
Never give a nephrotoxic medication on schedule when the level is already above target and the creatinine is climbing.
9Multiple choice, single answerLeadership and Management

The charge nurse needs to place a newly admitted client with HIV infection and an absolute neutrophil count of 450 cells/mm3 in a semi-private room. Which roommate is most appropriate?

A client with herpes zoster lesions on the chest that have not crusted
A client admitted yesterday with influenza and a fever
A client with cellulitis of the leg whose wound is draining
A client recovering from an uncomplicated hernia repair
Answer it, then check it.
Answer and rationale
Answer
  • D: A client recovering from an uncomplicated hernia repair
The key, and why
Human immunodeficiency virus (HIV) is a virus that attacks the immune system's CD4 cells, which help the body fight infection. A neutrophil count under 500 means this client is severely neutropenic and very vulnerable to infection. Ideally the client would have a private room. When a shared room is the only option, the roommate must be someone with no infection to pass on. The client recovering from an uncomplicated hernia repair, with no signs of infection, is the only safe choice here.
Each distractor
Option A has active shingles. The fluid in the blisters contains varicella-zoster virus, which can cause severe, widespread disease in an immunocompromised person. Option B has influenza, spread by droplets, which can be life-threatening in a client with very few neutrophils. Option C has a draining wound infection. The organisms in the drainage could spread to a client who cannot fight them.
The teaching point
NEUTROPENIC or immunocompromised client = PRIVATE room if possible. If shared, the roommate has NO infection: NOT shingles, chickenpox, flu, TB, draining wounds or C. difficile. Room assignment is a Management of Care decision for the RN.
10Multiple choice, single answerNutrition

The nurse is making a home visit to a 34-year-old client who is recovering from hepatitis A. The client usually cooks for a spouse and two school-age children. Which instruction should the nurse give to prevent spread of the infection to the family?

Use disposable plates and cups and discard them after every meal for the next 6 months
Boil the family's drinking water for 1 minute until the jaundice has completely resolved
Wash hands with soap and water after using the toilet and before preparing any food
Avoid sharing razors and toothbrushes, since the virus spreads mainly through blood contact
Answer it, then check it.
Answer and rationale
Answer
  • C: Wash hands with soap and water after using the toilet and before preparing any food
The key, and why
Hepatitis A is a viral infection of the liver that spreads by the fecal-oral route. The virus leaves the body in the stool and reaches the next person on unwashed hands, on food, or in water. A client is most contagious in the 2 weeks before the jaundice appears and stays contagious for about a week after it starts. For a client who cooks for the family, careful handwashing with soap and water after using the toilet and before touching food is the most important protection. Where possible, someone else does the cooking until the client is past the contagious period. The household contacts should also be offered the hepatitis A vaccine, which prevents illness when it is given within 2 weeks of exposure.
Each distractor
Option A is not needed. Dishes washed in hot, soapy water or a dishwasher are safe, and the client is no longer contagious after a few weeks, not 6 months. Option B does not address how the family would catch the virus. Treated tap water is not the risk at home. The risk is stool on the hands of the person preparing the food. Option D describes hepatitis B and C, which spread through blood and body fluids. Hepatitis A is spread by the fecal-oral route.
The teaching point
Hepatitis A = FECAL-ORAL. HANDWASHING with soap and water, especially before FOOD. Contagious 2 weeks BEFORE jaundice to about 1 week AFTER. Household contacts = hepatitis A VACCINE within 2 weeks.

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